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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF11
All Species:
30.91
Human Site:
Y399
Identified Species:
42.5
UniProt:
P52732
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52732
NP_004514.2
1056
119159
Y399
A
R
E
K
N
G
V
Y
I
S
E
E
N
F
R
Chimpanzee
Pan troglodytes
XP_507923
1056
119132
Y399
A
R
E
K
N
G
V
Y
I
S
E
E
N
F
R
Rhesus Macaque
Macaca mulatta
XP_001087644
853
96218
F239
S
S
R
S
H
S
V
F
S
V
T
I
H
M
K
Dog
Lupus familis
XP_534964
1334
149091
Y681
A
R
E
K
N
G
V
Y
I
S
E
E
N
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9P6
1052
118008
Y398
A
R
E
K
N
G
V
Y
I
S
E
E
S
F
R
Rat
Rattus norvegicus
O55165
796
89797
S182
V
Y
I
K
D
L
S
S
F
V
T
K
N
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
S378
H
G
G
T
L
P
V
S
I
N
S
M
A
P
S
Frog
Xenopus laevis
P28025
1060
119314
Y392
A
R
E
K
N
G
V
Y
L
S
S
E
N
Y
E
Zebra Danio
Brachydanio rerio
NP_775368
955
106984
N341
T
V
S
P
A
S
I
N
L
E
E
T
L
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46863
1066
121145
Y396
A
R
D
K
N
G
I
Y
L
A
E
E
T
Y
G
Honey Bee
Apis mellifera
XP_623508
706
80766
C92
E
V
L
A
G
Y
N
C
T
V
F
A
Y
G
Q
Nematode Worm
Caenorhab. elegans
P46873
699
78760
A85
G
Y
N
G
T
V
F
A
Y
G
Q
T
G
S
G
Sea Urchin
Strong. purpuratus
P46872
699
78679
I85
A
R
P
I
V
D
A
I
I
E
G
Y
N
G
T
Poplar Tree
Populus trichocarpa
XP_002314206
1066
119757
Y424
A
R
E
K
N
G
I
Y
I
P
R
D
R
Y
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P82266
1056
119250
Y399
S
R
E
K
N
G
V
Y
M
P
K
E
R
Y
Y
Baker's Yeast
Sacchar. cerevisiae
P28742
1111
125776
F450
S
R
N
K
Q
G
I
F
I
T
Q
D
Q
L
D
Red Bread Mold
Neurospora crassa
P48467
928
102392
D314
C
S
P
S
S
Y
N
D
A
E
T
L
S
T
L
Conservation
Percent
Protein Identity:
100
99.8
77.5
69.3
N.A.
79.7
23.3
N.A.
N.A.
25.3
56.2
47.7
N.A.
33.5
37.1
27.4
29.2
Protein Similarity:
100
99.9
79
73.8
N.A.
89
40.4
N.A.
N.A.
43.5
72.7
63.9
N.A.
55.4
52
42.5
42.8
P-Site Identity:
100
100
6.6
100
N.A.
93.3
13.3
N.A.
N.A.
13.3
73.3
6.6
N.A.
53.3
0
0
26.6
P-Site Similarity:
100
100
40
100
N.A.
100
33.3
N.A.
N.A.
20
86.6
20
N.A.
86.6
6.6
6.6
26.6
Percent
Protein Identity:
32.9
N.A.
N.A.
31.9
27.2
27.5
Protein Similarity:
52.3
N.A.
N.A.
51.5
48.6
45.5
P-Site Identity:
53.3
N.A.
N.A.
53.3
26.6
0
P-Site Similarity:
73.3
N.A.
N.A.
80
66.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
48
0
0
6
6
0
6
6
6
6
0
6
6
0
0
% A
% Cys:
6
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
6
6
0
6
0
0
0
12
0
0
6
% D
% Glu:
6
0
42
0
0
0
0
0
0
18
36
42
0
0
6
% E
% Phe:
0
0
0
0
0
0
6
12
6
0
6
0
0
24
0
% F
% Gly:
6
6
6
6
6
53
0
0
0
6
6
0
6
12
12
% G
% His:
6
0
0
0
6
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
0
0
6
6
0
0
24
6
48
0
0
6
0
0
0
% I
% Lys:
0
0
0
59
0
0
0
0
0
0
6
6
0
0
12
% K
% Leu:
0
0
6
0
6
6
0
0
18
0
0
6
6
6
12
% L
% Met:
0
0
0
0
0
0
0
0
6
0
0
6
0
6
0
% M
% Asn:
0
0
12
0
48
0
12
6
0
6
0
0
36
0
0
% N
% Pro:
0
0
12
6
0
6
0
0
0
12
0
0
0
6
0
% P
% Gln:
0
0
0
0
6
0
0
0
0
0
12
0
6
0
6
% Q
% Arg:
0
59
6
0
0
0
0
0
0
0
6
0
12
0
24
% R
% Ser:
18
12
6
12
6
12
6
12
6
30
12
0
12
12
6
% S
% Thr:
6
0
0
6
6
0
0
0
6
6
18
12
6
6
12
% T
% Val:
6
12
0
0
6
6
48
0
0
18
0
0
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
12
0
48
6
0
0
6
6
24
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _